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Links 1 through 10 of 27 by NAPWHA tagged interactions

The antiviral drug Telzir should not be used together with some drugs to treat irregular heartbeat or another specific anti-viral medication used to treat HIV infection, Health Canada warns.

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Blood levels of MK-1439, a next-generation HIV non-nucleoside reverse transcriptase inhibitors (NNRTI) in phase 2b trials, rose significantly when combined with ritonavir, but tenofovir had little effect, researchers reported at the 53rd Interscience Conference on Antimicrobial Agents and Chemotherapy last week in Denver.

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The US FDA recently approved updates to the Atripla (efavirenz/emtricitabine/tenofovir disoproxil fumarate) tablet label to include several changes relating to side effects, drug interactions and breastfeeding.

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There is no evidence of an interaction between the anti-HIV drug abacavir and the anti-hepatitis C agent ribavirin, investigators report in the online edition of AIDS.

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The commonly prescribed anticoagulant warfarin is highly susceptible to interactions with antiretroviral mediated through CYP 2C9, 2C19, and/or 3A4 pathways, although data are limited.

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Medicine regulatory authorities in the US have updated their recommendations concerning possible interactions between statins and protease inhibitors used to treat HIV and hepatitis C.

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Health care providers are being reminded not to prescribe certain cholesterol-reducing medications—notably members of the “statin” drug class—for people living with hepatitis C virus (HCV) using either Incivek (telaprevir) or Victrelis (boceprevir), according to a recent U.S. Food and Drug Administration (FDA)safety announcement.

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An international Hep C activist group is calling on government regulators and pharmaceutical companies developing therapies for hepatitis C virus (HCV) infection to conduct necessary interaction studies involving other medications commonly used by people living with HCV and HIV/HCV coinfection as early as possible.

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Merck & Co's recently approved Victrelis treatment for hepatitis C considerably lessens the effectiveness of some widely used medicines against the virus that causes AIDS, Merck and U.S. regulators said in separate reports.

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New guidelines from the American Academy of Neurology (AAN) and the International League Against Epilepsy (ILAE) have been published online ahead of print by the journal Neurology to help people living with HIV and their care providers choose seizure drugs that do not interact negatively with antiretrovirals (ARVs).

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